2 Aralık 2012 Pazar

Surgical Treatment of Gastric Cancer


Surgical treatment of gastric cancer

The only curative treatment is surgical resection of gastric cancer. Other treatments consist of surgical resection followed by adjuvant therapy and palliative treatment with chemotherapy, radiotherapy and immunotherapy followed. Today, with the development of diagnostic tools for staging work and staging accuracy of 80% - to reach 85%. R0 resection, if surgical treatment is to target. Curative resection in patients without distant metastases, peritoneal dialysis and lymph node metastases in pathological by all and clear surgical margins by eliminating extravagance stomach. Radical gastrectomy or distal subtotal gastrectomy can be achieved if surgical margins were clean as yours. If the upper limit should tumor, the greater curvature side of the intersection with the left and right gastroepiploic artery, from below the line of curvature at the lower side of the cardia and gastrectomy be 5cm.
Complications Surgery Stomach Cancer
Gastric cancer resection with different complications can develop in approximately 20% of patients. Careful preoperative preparation, surgery is a good post-operative care and maintenance of the technical underpinnings of the stomach and reducing complications after surgery is possible. Complications after surgery for stomach cancer as surgical complications and general complications are classified.
Major postoperative complications and surgical bleeding, duodenal stump leak and anastomotic leaks. Duodenal stump leakage is a major complication of morbidity and mortality in the postoperative period.


How is my body in gastric cancer

How is it spread to the body of stomach cancer

Howell through dissemination of gastric cancer since the publication in 1932, Cornett and is defined as follows:
1.Direk Propagation mucosa submucosa invasion of cancer that starts in the first, then a muscle involvement and subserosa. Esophagus and duodenum is the direction of propagation of this mode. Run through the muscle layer of the duodenum, and subserosal lymphatics. Run through all layers of the esophagus is usually olabilmekle through the submucosal lymphatics.

2.Peritoneal propagation: along the stomach wall can transmit peritoneal serous tumors reach. Diffuse peritoneal cancer, colon tip and is more common than you.
Propagation 3.Hematojen: organ metastases develop in this way. Hematogenous spread is the most common liver. Very often diffuse intestinal type adenocarcinomas type tend to spread hematogenously.

Propagation 4.Lenfatik: Stomach cancer, lymphatic invasion begins early. If the lymph node resection rate of 50%. Reported 1241 study examined patients with all stages of lymph node positivity as 76.5% Kennedy. Particularly in the lymphatic invasion 4cm'den submucosal invasion is an increased risk of large, poorly differentiated tumors. Obana et al lymph nodes morphologically divided into two subgroups. The presence of tumor emboli in the style of lymph nodes and paths exist or embolic types of cancer cells have a lymphoid tumor cell interstitial areas adipose tissue around the tumor and lymph nodes is defined herein as a kind of infiltration. Embolic metastasis from intestinal-type gastric cancer, metastatic infiltrating type is more common in diffuse gastric cancer.

Microscopic characteristics of stomach cancer


Microscopic characteristics of gastric carcinoma

A significant portion of the gastric mucosa, intestinal metaplasia in the cellular basis of the diversity and the development of tumors, these tumors have a variety of causes morphological. Stomach Adenokarsinomlarını WHO recognizes four histological types. Further, the size and depth of invasion of gastric cancer increases with increasing histologic diversity. According to the WHO classification of the pathological diagnosis of gastric cancer according to the predominant histological characteristics is performed. However, the predominant histologic feature of gastric cancer is not the true nature of mixed histologic pattern. Another approach to test the histologic classification of gastric dysplasia. WHO in 2000 was for all GIS concept of dysplasia and not as "intraepithelial neoplasia" more appropriate to use the concept does not explain and define intraepithelial neoplasia lesions and stromal invasion.
According to the WHO classification of tumors, when the diagnosis of invasive adenocarcinoma If infiltration of the lamina propria and submucosa. The literature shows the progress of high-quality diagnosis of prostatic intraepithelial neoplasia invasive adenocarcinoma of the stomach in relation to studies with a follow up of the patients examined, it was found that most studies of invasive carcinoma within a few months. What is known is the molecular point of view different from the genetically very high grade intraepithelial neoplasia invasive carcinoma.

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